Title |
ANTIMICROBIAL ACTIVITY OF MIXTURE FROM DIFFERENT PLANT EXTRACTS IN GEL, CREAM AND BODY MILK FORMULATION, AGAINST DIFFERENT MICROORGANISMS |
Author/s |
Dzoko Kungulovski, Natalija Atanasova-Pancevska |
Citation |
Dz. Kungulovski, N. Atanasova-Pancevska, "ANTIMICROBIAL ACTIVITY OF MIXTURE FROM DIFFERENT PLANT EXTRACTS IN GEL, CREAM AND BODY MILK FORMULATION, AGAINST DIFFERENT MICROORGANISMS",
Contributions, Sec. Nat. Math. Biotech. Sci., MASA, ISSN 1857-9027, Vol. 35, no.2, 2014, pp.139-146. |
Abstract |
In this study the antimicrobial activity of a mixture of plant extracts originating from five different plants
and suspended in three different forms of gel, cream and lotion was examined with the purpose of discovering new
antimicrobial compounds. The antimicrobial activity was investigated through the standard disc diffusion method, as well
as through a variation of the microdillution method. The formulations under examination (gel, cream and lotion)
showed a broad spectrum of action against all the selected microorganisms, with inhibition zones of 9–46 mm. The
minimal inhibitory concentration (MIC) for all the formulations against the microorganisms in the study was in the
range of 0.000761μg ml-1 to 0.125μg ml-1. The results of this study have clearly demonstrated that the mixture of
plant extracts originating from five different plants and suspended in the forms of gel, cream and lotion can definitely
be used in the battle against the microorganisms under investigation.
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Keywords |
antimicrobial activity; plant extracts; disk-diffusion method; microdilution method |