| Title | DO SPLEEN MACROPHAGE AGGREGATES UNDERGO SEASON-DEPENDENT CHANGES? A STEREOMICROSCOPIC INVESTIGATION IN WILD OHRID TROUT (SALMO LETNICA KAR.) |
| Author/s | Katerina Rebok, Irena Tavčiovska-Vasileva, Maja Jordanova |
| Citation | K. Rebok, I. Tavčiovska-Vasileva, M. Jordanova, "DO SPLEEN MACROPHAGE AGGREGATES UNDERGO SEASON-DEPENDENT CHANGES? A STEREOMICROSCOPIC INVESTIGATION IN WILD OHRID TROUT (SALMO LETNICA KAR.)", Contributions, Sec. Nat. Math. Biotech. Sci., MASA, ISSN 1857-9027, Vol. 36, no.1, 2015, pp.11-17. |
| Abstract | In past decades macrophage aggregates (MACs) were being used in many monitoring studies as useful immu-nological biomarkers of environmental pollution and they are still encountered in the so-called “future biomarkers”, since quantitative studies in aquaculture and/or field of their normal fluctuations as a result of the influence of natural factors are extremely rare. Our investigation was designed to quantitatively evaluate the influence of the seasons on MAC's relative volume, number and diameter in the Ohrid trout (Salmo letnica Kar.) spleen. Data showed that all investigated parameters had significantly higher values in fish collected during spring and winter. Correlation anal-yses revealed that the increasing of the relative volume of MACs is a result of the increasing of the relative volume of melanin loaded MACs, as well as the increasing of their number and diameter. These results confirmed that the sea-son can affect MACs variations and should be taken into consideration, especially when spleen MACs are used as pollution biomarkers in monitoring studies. |
| Keywords | hybrid nanofiller; carbon nanotubes; montmorillonite; dispersion |
